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The study identifies viral exmiRs as markers for live virus infection in T cells. Purified T cells were activated and cultured in a G-Rex® 24-well plate.

This study profiles CAR T cells across manufacturing. Transductions and expansion were carried out in G-Rex® 6M vessels to support high-density cell growth.

The authors developed an efficient protocol for expanding CAR-T and CIK cells using G-Rex® 24 and G-Rex® 6M devices. The study highlights the scalability and high cell yield obtained using these gas-permeable culture systems.

The study reports the optimized GMP-grade manufacturing of TranspoCART19 cells. Following electroporation, cells were expanded for 11 days in G-Rex® 100M devices, achieving high expansion and functionality.

This study develops AI models to quantify TILs in colorectal cancer liver metastasis. In the Rapid Expansion Protocol (REP) stage, TILs were cultured in G-Rex® 100 M.

Tmod cells maintain robust potency and selectivity. Transduced cells were cultured in G-Rex® 24 well plates, and T cells for in vivo studies were cultured in G-Rex® 6 well plates.

The study presents a 24-hour CAR-T manufacturing workflow. T cell cultures were maintained in G-Rex® vessels during isolation and transduction, and control 7-day expansions were also performed in G-Rex® vessels.

This review discusses cost-effective CAR-T manufacturing. It highlights G-Rex® technology as a main point-of-care (POC) manufacturing platform that enables high cell density production at lower costs compared to fully automated systems.

PF-07260437 demonstrates potent antitumor efficacy in breast cancer models. For adoptive T cell transfer studies, human T cells were expanded in a G-Rex® cell culture device.

This study explores combining CAR T cells with 177Lu-DOTATATE targeted radionuclide therapy. CAR T cells were transduced and subsequently expanded in G-Rex® 6M well plates.

The study describes the preclinical evaluation of TAC01-CLDN18.2 T cells. These cells were manufactured using purified CD4/CD8 T cells in a 9-day process utilizing either the G-Rex® system from Wilson Wolf or the Cocoon platform.

This paper reports a method leveraging HMEJ for Cas9-induced targeted integration of large DNA payloads. In the lentiviral transduction comparison arm, T cells were activated and transferred to a G-Rex® 24-well plate for expansion.