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Publications
B Cells, CAR T Cells, T-Cells, TCR T Cells
G-Rex100M-CS, G-Rex6M – 10cm²
Integrated T-Cell Enrichment, Static Transduction, and Expansion in Gas-Permeable Bioreactors for Adoptive Cell Therapy
This study details an integrated, closed CAR T-cell manufacturing workflow. The process utilizes a G-Rex 100M-CS bioreactor for direct in-vessel CD4+/CD8+ magnetic enrichment using a prototype SepaRex base, static retroviral transduction, and T-cell expansion, eliminating separate selection or spinoculation devices.
Publications
CAR T Cells
Single-Use, Metabolite Absorbing, Resonant Transducer (SMART) Culture Vessels for Label-Free, Continuous Cell Culture Progression Monitoring: Supplemental Figures
This document provides supplemental data for the SMART culture vessel study. It details chemical solvents, concentrations, liposome additions, and experimental controls like phosphate-buffered saline. G-Rex is not explicitly referenced in this supplemental document.
Publications
CAR T Cells
Single-Use, Metabolite Absorbing, Resonant Transducer (SMART) Culture Vessels for Label-Free, Continuous Cell Culture Progression Monitoring
This article details a single-use metabolite absorbing resonant transducer (SMART) for continuous cell culture monitoring. Polyacrylate films absorb secreted metabolites, altering sensor permittivity. G-Rex10 static culture vessels are explicitly referenced for validating sensor sensitivity to live cells.
Publications
Other
Low-Cost Portable Readout System Design for Inductively Coupled Resonant Sensors
This paper proposes a low-cost, portable readout system to wirelessly interrogate LC resonant sensors. Using coherent demodulation and a direct digital synthesizer, the system successfully tracks temperature changes in water. G-Rex is not referenced in this document.
Publications
Other
G-Rex10M
Contact-Free, Passive, Electromagnetic Resonant Sensors for Enclosed Biomedical Applications: A Perspective on Opportunities and Challenges
This review discusses contact-free, passive electromagnetic resonant sensors for biomedical applications. It highlights challenges like environmental noise and positional sensitivity, proposing differential sensors to increase specificity. G-Rex is not referenced in this document.
Publications
CAR T Cells, T-Cells
G-Rex100M
SMART Sensors for Cell Growth Monitoring in Closed System G-Rex: Supplemental Figures
This document provides supplemental data on the SMART sensor in G-Rex devices. It evaluates sensor responses to T cell-secreted metabolites, kerf width effects, and reader hardware temperature impact. G-Rex 100M is explicitly referenced as the cell culture vessel used for these tests.
Publications
CAR T Cells, T-Cells
G-Rex100M, G-Rex100M-CS, G-Rex500M
SMART sensors for cell growth monitoring in closed system G-Rex for scalable, cost-conscious cell and gene therapy manufacturing
This article describes integrating a SMART sensor into the G-Rex bioreactor for real-time, noninvasive monitoring of cell expansion. G-Rex devices, including the G-Rex 100M and 500M, are explicitly referenced as the core manufacturing platform for scaling CAR-T cell production.
Publications
Other
Kirigami-Enabled, Passive Resonant Sensors for Wireless Deformation Monitoring
This paper presents a kirigami-enabled passive resonant sensor to wirelessly monitor material deformation. The sensor responds to stretching via changes in capacitance and inductance. The study evaluates sensor gain and flow rate monitoring. G-Rex is not referenced in this document.
