Videos
Ignacio Núñez, COO, CellReady, Discusses Sustainability in Cell Therapy at ISCT 2024
Ignacio Nunez, COO of CellReady, discusses the importance of sustainability in cell and gene therapy manufacturing at ISCT 2024.
Videos
Ignacio Núñez, COO, CellReady, Discusses Current Projects at ASGCT 2024
Ignacio Nunez, COO of CellReady, discusses current projects and what the future holds during ASGCT 2024.
Videos
ISCT 2024: Redefining Sustainability in CGT, Ensuring Patient Affordability and Accessibility
Leading industry experts discuss critical strategies to make life-changing treatments more accessible and affordable for patients during ISCT 2024. Hear from top executives at Germfree, Cellular Origins, and CellReady as they discuss innovative solutions to overcome industry challenges. Moderated by ScaleReady.
Scientific Posters
G-Rex Bioreactors and Heracell Vios Incubators and Cross Contamination Prevention
For Cell and Gene Modified Cell Therapy (CGT) manufacturing, a robust contamination control strategy (CCS) is necessary to ensure compliance with current Good Manufacturing Practices (cGMP). A successful CCS helps ensure safety, purity, efficacy, and quality of a CGT product. CGT manufacturers should implement Closed Systems wherever possible and employ equipment that maintains a stable, clean environment with advanced monitoring. We show that Closed System G-Rex® bioreactors combined with Thermo ScientificTM HeracellTM ViosTM CR carbon dioxide (CO2) incubators enable simplified parallel processing capabilities and significantly reduced contamination risks in a highly efficient production.
Videos
Ignacio Núñez, COO, CellReady, Discusses Partnership with ScaleReady at ISCT 2024
Rizwan Chaudrey spoke with Ignacio Núñez, COO, CellReady, at ISCT 2024 about the company, its relationship with ScaleReady, what they are showcasing tat ISCT and what makes them unique.
Literature
ExCellerateTM T Cell Media Animal Component-Free Flyer
ExCellerate T Cell Media supports robust ex vivo CD3+ T cells, while maintaining high viability. This media is optimized to be used with Bio-Techne R&D SystemsTM cytokines and is compatible Excellerate media is compatible with closed system G-Rex bioreactors.
Application Notes
Avectas Solupore® and G-Rex® Platform App Note
In this application, the health of Triple Knock-Out (KO) transfected T-cells was evaluated by measuring cell expansion and viability in a Gas Permeable Rapid Expansion (G-Rex® - Wilson Wolf Manufacturing, LLC) platform using different cell culture media and cytokine supplement.
Literature
G-Rex Grant Program Flyer
The G-Rex® Grant Program is empowering CGT manufacturers with resources and expertise and is a $20 million initiative by ScaleReady, Wilson Wolf Manufacturing, Bio-Techne, and CellReady, that is designed to propel the advancement of cell and gene therapies (CGT). If you’re engaged in pre-clinical research, process development, or cGMP manufacturing of cell and gene-modified cell therapies, this program is for you!
Literature
G-Rex Grant Program Outline
Review the official description and outline of the new G-Rex® Grant Program, which empowers CGT manufacturers with resources and expertise. This $20 million initiative by ScaleReady, Wilson Wolf Manufacturing, Bio-Techne, and CellReady is designed to propel the advancement of cell and gene therapies (CGT).
Videos
Multiply Labs and Wilson Wolf Collaborate to Automate G-Rex for Cell Therapy Manufacturing
Multiply Labs, a robotics company developing industry-leading automated manufacturing systems to produce individualized drugs, and Wilson Wolf, an innovative leader in cell and gene-modified cell (CGT) manufacturing technology, today announced a collaboration around the automation of Wilson Wolf’s G-Rex® bioreactors.
CUE, LOVO, Scientific Posters
AgonOx Cell Therapy Manufacturing Process Scientific Poster
To better optimize their manufacturing process for a current clinical trial and IND amendment, AgonOx and Providence began to look for products to close and streamline key portions of the established manufacturing process for a shared project. It was imperative to find products that would maintain established levels of cell recovery, viability, and efficacy.
Application Notes
Analytical Tools to Evaluate CAR-T Cell Signaling & Activation App Note
CAR-T cell therapy has emerged as a powerful weapon in the fight against specific B-cell malignancies. Its success has fueled significant research efforts to broaden its reach to encompass a wider range of hematologic and solid tumors.
Optimizing CAR-T cell therapy hinges on a deeper understanding of the intricate signaling pathways that govern these potent immune cells. This includes their ability to infiltrate tumors, evade antigen escape mechanisms, resist immunosuppression, and minimize potentially fatal toxicities. To achieve this, researchers require a comprehensive characterization of the signaling molecules involved, encompassing the extracellular, membrane-bound, and intracellular compartments. However, this endeavor is often hampered by limited and complex sample types.
The Wilson Wolf G-Rex platform offers a unique solution for large-scale expansion of CAR-T cells, enabling researchers to study these vital communication networks within larger, more robust cell populations. This facilitates a deeper understanding of CAR-T cell function and paves the way for the development of safer and more effective CAR-T therapies.
Unleash the Full Potential of CAR-T Cells: Learn More
Understanding these vital communication networks within CAR-T cells is critical to unlocking their full potential. Download our free App Note: Analytical Tools to Evaluate CAR-T Cell Signaling & Activation to explore the latest advancements in research methods for optimizing CAR-T cell therapy.