Workflow

The complete ScaleReady workflow: how everything fits into one scalable process

Built around the breakthrough advantages of G-Rex® closed-system bioreactors, the ScaleReady workflow was created specifically to produce immune cells such as T cells, natural killer (NK) cells, and hematopoietic cells. True linear scalability means that the same protocols established during research will work during large-scale production.

Cell Activation & Expansion

G-Rex closed-system bioreactors are the only system that scales up from 10 million to over 100 billion cells without gene profile changes, and scale out with one bioreactor per patient. Within a single G-Rex bioreactor cells can be activated, transduced, and expanded, dramatically simplifying manufacturing processes. Combine G-Rex with high-quality GMP media, activation reagents and cytokines sourced from Bio-Techne.

G-Rex100M-CS

500×500 NK Media

500×500 STP Cytokines

Gene Editing

The TcBusterTM non-viral gene delivery platform makes gene modification more consistent, faster, and cost-efficient, without the challenges involved in manufacturing lentiviral vectors.

Culture Harvest

The GatheRex liquid handling pump is thoughtfully designed to work with any G-Rex bioreactor for simple volume reduction and cell harvesting.

Get in touch to begin scaling up and scaling out.

The Lovo and Cue Cell Processing Systems are for laboratory use only and may not be used for direct transfusion. Appropriate regulatory clearance is required by the user for clinical use.

For applications requiring regulatory clearance or approval, Users may request the required technical documentation from Fresenius Kabi to support their submissions.

Refer to the Lovo Cell Processing System Operator’s Manual, Cue Cell Processing System User’s Guide, DXT Administrator’s Guide and DXT User’s Guide for a complete list of warnings and precautions associated with the use of these products.