GMP-Grade Animal-Free Recombinant Human IL-2 for Cell Therapy Manufacturing
IL-2 RUO and GMP Animal-Free Cytokines
We source Bio-Techne R&D Systems RUO and GMP-grade IL-2, which contains the same cysteine to serine mutation found in Proleukin®. This mutation has been reported to prevent cysteine mispairing in E. coli, which can lead to protein aggregation and make our new GMP-grade IL-2 protein soluble in injectable-grade water.
CGT researchers use IL-2 GMP proteins to promote the proliferation of CAR-T cells, TCR T cells, Tregs, TILs, and NK and CIK cells. Our Animal-Free GMP-grade cytokines boast robust reproducible bioactivity and confidence in RUO to GMP translation that will accommodate closed-system requirements as you progress through clinical trials.
Dedicated Facility - USA Based
Working with Bio-Techne R&D proteins means working with truly animal-free devoid of animal contaminants and mammalian pathogens. Our proteins are produced in the only publicly known state-of-the-art certified animal-free facility at our St. Paul, Minnesota, USA headquarters. Animal-free certificates of origin are available, and traceable batch records are kept for all our recombinant human GMP cytokines.
Have confidence in your cytokines to meet the growing industry demand and the needs of your program from process development to commercialization. The new facility is not only animal-free, it has been optimized for scale to address these challenges.
No More Reconsitution! Save Time with Liquid Cytokines!
- Streamlined Process: Save time and materials – no reconstitution
- Increased Reproducibility: Eliminate errors with reconstitution steps
- Equivalent Bioactivity: Easily substitute for lyophilized proteins
- Stability: Rely on full bioactivity for at least six months as supplied.
Save Precious Time and Burn Less Cash
Prevent the time lost and money invested in re-qualifying lots. Entire lots of our animal-free IL-2 can be reserved to accommodate your long-term program needs all while being rigorously tested to ensure consistency with previous lots and master lots so your confidence in product continuity remains high.
Animal Free IL-2 RUO to GMP Scalable, Seamless Translation
Scaling up from research to clinical can present many challenges, but your confidence in cytokine performance shouldn’t be one of them. Your program needs supply chain security, and assurance of consistent RUO to GMP bioactivity all while moving with speed and efficiency… and to do so shouldn’t have any compromise.
High bioactivity and low lot-to-lot variability mean confidence in your cytokine experiments that are reproducible over time, speeding up the entire process all while lowering overall risk.
Choose IL-2 Cytokine Formats that Fit Your Need
Bio-Techne GMP cytokines are available in off-the-shelf vials in 50μg, 1mg sizes, and custom mass/vial (liquid or lyophilized).
Secure your IL-2 RUO or GMP animal-free proteins today, fill out the form below to test cytokines in your program and we’ll be in touch!
How to order
Testimonials
- Michael Paglia
Chief Operating Officer
Elevate Bio, BaseCamp