We source Bio-Techne R&D Systems RUO and GMP-grade IL-2, which contains the same cysteine to serine mutation found in Proleukin®. This mutation has been reported to prevent cysteine mispairing in E. coli, which can lead to protein aggregation and make our new GMP-grade IL-2 protein soluble in injectable-grade water.
CGT researchers use IL-2 GMP proteins to promote the proliferation of CAR-T cells, TCR T cells, Tregs, TILs, and NK and CIK cells. Our Animal-Free GMP-grade cytokines boast robust reproducible bioactivity and confidence in RUO to GMP translation that will accommodate closed-system requirements as you progress through clinical trials.
Working with Bio-Techne R&D proteins means working with truly animal-free devoid of animal contaminants and mammalian pathogens. Our proteins are produced in the only publicly known state-of-the-art certified animal-free facility at our St. Paul, Minnesota, USA headquarters. Animal-free certificates of origin are available, and traceable batch records are kept for all our recombinant human GMP cytokines.
Have confidence in your cytokines to meet the growing industry demand and the needs of your program from process development to commercialization. The new facility is not only animal-free, it has been optimized for scale to address these challenges.
Prevent the time lost and money invested in re-qualifying lots. Entire lots of our animal-free IL-2 can be reserved to accommodate your long-term program needs all while being rigorously tested to ensure consistency with previous lots and master lots so your confidence in product continuity remains high.
Scaling up from research to clinical can present many challenges, but your confidence in cytokine performance shouldn’t be one of them. Your program needs supply chain security, and assurance of consistent RUO to GMP bioactivity all while moving with speed and efficiency... and to do so shouldn’t have any compromise.
High bioactivity and low lot-to-lot variability mean confidence in your cytokine experiments that are reproducible over time, speeding up the entire process all while lowering overall risk.
Bio-Techne GMP cytokines are available in off-the-shelf vials in 50µg, 1mg sizes, and custom mass/vial (liquid or lyophilized).
Secure your IL-2 RUO or GMP animal-free proteins today, fill out the form below to test cytokines in your program and we’ll be in touch!
