Feeder-Cell-Free and Serum-Free Expansion of Natural Killer Cells Using Cloudz Microspheres, G-Rex6M, and Human Platelet Lysate
The authors developed a feeder-free, xeno-free protocol for NK cell expansion using NK Cloudz microspheres in G-Rex6M vessels with human platelet lysate. The method achieved ~387-fold expansion in 10 days with high purity and cytotoxicity, offering a scalable alternative to feeder cell-based methods.
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