Knowledge HQ

Publications

Manufacture of GMP-grade Cytotoxic T Lymphocytes specific for LMP1 and LMP2 for Patients with EBV-associated Lymphoma

Outlines GMP manufacturing of LMP1/LMP2-specific CTLs for EBV-associated lymphoma. Describes using G-Rex devices for the second stimulation and expansion phases to support high-density cell growth. G-Rex simplifies the process and reduces labor compared to traditional 24-well plates while maintaining cell quality
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Publications

Accelerated Production of Antigen-specific T Cells for Preclinical and Clinical Applications Using Gas-permeable Rapid Expansion Cultureware (G-Rex)

Evaluates G-Rex for expanding antigen-specific CTLs. G-Rex supports 3-20 fold higher cell output than 24-well plates by improving gas exchange and allowing deeper media. The device simplifies manufacturing by reducing interventions and supports high-density culture of CTLs and CAR-T cells without compromising function
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Publications

Improved Islet Culture on Top of Gas-Permeable Membranes

Investigates culturing pancreatic islets on gas-permeable silicone rubber membranes. This method allows for higher surface densities (up to 4000 IE/cm²) and media depths compared to standard without hypoxic damage. G-Rex technology principles are tested here for islet survival and function
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Literature

Ready to Use Cytokines -Closed System

Speed up your immune cell therapy manufacturing with Ready-to-Use GMP Cytokines. Now available in three convenient formats—ProPak closed system bags, process-sized vials, and liquid formulations—these high-quality cytokines eliminate unnecessary steps, reduce handling errors, and ensure consistency in your workflow. Whether you're optimizing T cell expansion or streamlining cytokine delivery, our animal-free GMP and RUO proteins are designed for efficiency and reliability. Download this flyer to see how you can enhance your process and accelerate your path to the clinic with ease.
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Literature

NK Media Flyer - Accelerate Development

Unlock the full potential of NK cell therapies with ExCellerate™ NK Cell Expansion Media—a cutting-edge, animal-free solution designed to streamline your research and clinical applications. Whether you're working with iPSC-derived NK cells, PBMCs, or purified NK cells, this innovative media ensures robust expansion, sustained viability, and optimized cytotoxic function without the complexities of traditional serum-based systems. Ready to accelerate your NK cell research with a simplified, high-performance solution? Download the flyer now to see how ExCellerate™ can enhance your workflow and drive better results.
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Videos

GatheRex Closed System Harvest

Videos

ATW 2025 ScaleReady and Ignacio Nunez COO CellReady with Cellular Origins - Key Partnerships in CGT

Ignacio Nunez discusses the importance of collaboration and partnerships, such as that between ScaleReady and Cellular Origins, and the impact of these on drug development and patient accessibility.
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Videos

G-Rex vs Rocking Motion Bio-Reactors

The best technology is often the simplest. Quiet, elegant, brilliant. A revolution in T-Cell culture technology. The G-Rex Bioreactor.
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Application Notes

Fill and Forget Application Note

Discover a game-changing approach to T cell expansion. This application note showcases how the G-Rex bioreactor and Bio-Techne reagents deliver hands-free, zero-touchpoint cell growth. Learn how to streamline your manufacturing, boost efficiency, and maintain cell health—all with a simple fill-and-forget workflow.
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Videos

Ignacio Núñez, COO, CellReady, Discusses Sustainability in Cell Therapy at ISCT 2024

Ignacio Nunez, COO of CellReady, discusses the importance of sustainability in cell and gene therapy manufacturing at ISCT 2024.
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Videos

Ignacio Núñez, COO, CellReady, Discusses Current Projects at ASGCT 2024

Ignacio Nunez, COO of CellReady, discusses current projects and what the future holds during ASGCT 2024.
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Videos

ISCT 2024: Redefining Sustainability in CGT, Ensuring Patient Affordability and Accessibility

Leading industry experts discuss critical strategies to make life-changing treatments more accessible and affordable for patients during ISCT 2024. Hear from top executives at Germfree, Cellular Origins, and CellReady as they discuss innovative solutions to overcome industry challenges. Moderated by ScaleReady.
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