Signaling via a CD28/CD40 chimeric costimulatory antigen receptor (CoStAR™), targeting folate receptor alpha, enhances T cell activity and augments tumor reactivity of tumor infiltrating lymphocytes
The study demonstrates that CoStAR, a chimeric costimulatory receptor, enhances the effector function of T cells and TILs. Transgene-expressing cells and TILs were expanded using G-Rex plates, including G-Rex 6M, as part of the rapid expansion protocol.
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